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pentobarbital will lessen the extent or outcome of bexarotene by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.pentobarbital will decrease the extent or outcome of rabeprazole by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Unknown.pentobarbital decreases levels of toremifene by affecting hepa